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Congratulations to Hongji Yan and Cristina Chircov from the group for publishing their work entitled Reversible Condensation of Mucins into Nanoparticles in the ACS journal Langmuir. You may access the articles for free here (and through our website)

This work started with the visit of Cristina Chircov on a bachelor internship funded by an Erasmus fellowship. Cristina and Hongji found that by adding glycerol to dilute solutions of mucins, one could induce a drastic compaction of the molecules, from 1000 nm to only tens of nm. They found the effect was reversible and could be partially stabilized by cationic crosslinkers.

This work is the result of a nice collaborative effort, with strong participation from colleagues of the division of surface and corrosion sciences at KTH, the team of Hans Herbert at KTH and the team of Prof. Lieleg at TUM. We are continuing this project with the ambition to fully stabilize the nanoparticles once transferred out of the glycerol solution and build in environmental triggers to enable their sudden swelling.

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  Posts

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November 19th, 2018

New publication: Reversible Condensation of Mucins into Nanoparticles

October 15th, 2018

Welcome to Gilai and Laise

July 30th, 2018

New review published: Mucins as multifunctional building blocks of biomaterials

July 9th, 2018

New publication: Muco-silk, an mucoadhesive engineered silk

June 26th, 2018

Thank you to the master and bachelor students of Spring 2018!!

March 7th, 2018

New mucus engineering publication from the group.

January 26th, 2018

Welcome to three new students!

August 21st, 2017

iGEM Stockholm 2017 engineering mucus – Update with gold!

August 18th, 2017

Welcome to Ulrike Schimpf and Cristina Chircov!

July 13th, 2017

Mucin-inspired lubrication on hydrophobic surfaces