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Congratulations to Hongji Yan and Cristina Chircov from the group for publishing their work entitled Reversible Condensation of Mucins into Nanoparticles in the ACS journal Langmuir. You may access the articles for free here (and through our website)

This work started with the visit of Cristina Chircov on a bachelor internship funded by an Erasmus fellowship. Cristina and Hongji found that by adding glycerol to dilute solutions of mucins, one could induce a drastic compaction of the molecules, from 1000 nm to only tens of nm. They found the effect was reversible and could be partially stabilized by cationic crosslinkers.

This work is the result of a nice collaborative effort, with strong participation from colleagues of the division of surface and corrosion sciences at KTH, the team of Hans Herbert at KTH and the team of Prof. Lieleg at TUM. We are continuing this project with the ambition to fully stabilize the nanoparticles once transferred out of the glycerol solution and build in environmental triggers to enable their sudden swelling.

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  Posts

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February 27th, 2019

New video of our work

January 7th, 2019

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January 2nd, 2019

Protein Materials Conference 7-8th March 2019

December 13th, 2018

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November 19th, 2018

New publication: Reversible Condensation of Mucins into Nanoparticles

October 15th, 2018

Welcome to Gilai and Laise

July 30th, 2018

New review published: Mucins as multifunctional building blocks of biomaterials

July 9th, 2018

New publication: Muco-silk, an mucoadhesive engineered silk

June 26th, 2018

Thank you to the master and bachelor students of Spring 2018!!

March 7th, 2018

New mucus engineering publication from the group.